Here is some great insight from John Piper. John Piper was born in Chattanooga, Tennessee, to Bill and Ruth Piper January 11, 1946. Desiring God began inauspiciously in 1994 when John handed off the church’s tape ministry to his assistant, Jon Bloom. What started with tapes and John’s books, Desiring God has blossomed into an international web ministry with 12,000+ free resources and 3.5+million monthly users. Today, John serves as lead teacher for the ministry.
I believe that the Bible teaches that God made us male or female, and no matter our own feelings or confusion, we should act in accordance with the biological reality of God’s good design. Transgenderism falls short of the glory of God and is not the way to walk in obedience to the Messiah.
Power of the Holy Spirit 
John Piper is helpful
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